This standard specifies the diagnostic criteria and treatment principles for occupational melanosis. This standard applies to the diagnosis and treatment of occupational melanosis. GBZ 22-2002 Occupational melanosis diagnostic criteria GBZ22-2002 Standard download decompression password: www.bzxz.net

ICS13.100
National Occupational Health Standard of the People's Republic of China GBZ22—2002
Diagnostic Criteria of Occupational Melanosiswww.bzxz.net
Diagnostic Criteria of Occupational Melanosis2002-04-08 Issued
Ministry of Health of the People's Republic of China
Implementation on 2002-06-01
Article 4.1 of this standard is recommended, and the rest are mandatory. This standard is formulated in accordance with the "Law of the People's Republic of China on the Prevention and Control of Occupational Diseases". From the date of implementation of this standard, if there is any inconsistency between the original standard GB7808-1987 and this standard, this standard shall prevail. Occupational melanosis is a skin pigment change caused by occupational factors, which mostly occurs in middle-aged people, more in women than in men, and can occur in various industries and types of work. This standard is formulated to protect the health of contacts and effectively prevent and treat occupational skin diseases. Appendix A of this standard is an informative appendix.
This standard is proposed and managed by the Ministry of Health of the People's Republic of China. This standard was drafted by the Institute of Occupational Health and Poison Control of the Chinese Center for Disease Control and Prevention, the Second Hospital of Changchun, the Shanghai Dermatology and Venereology Hospital, the Second Medical University of Shanghai, and the Shandong Provincial Institute of Occupational Health and Occupational Disease Prevention and Control. The Ministry of Health of the People's Republic of China is responsible for interpreting this standard. Occupational melanosis diagnostic criteria
GBZ22-2002
Occupational melanosis refers to a chronic skin pigmentation disease caused by occupational harmful factors (mainly coal tar, petroleum and its fractionation products, rubber additives, certain pigments, dyes and their intermediates, etc.) in the labor or working environment. 1 Scope
This standard specifies the diagnostic criteria and treatment principles for occupational melanosis. This standard is applicable to the diagnosis and treatment of occupational melanosis. 2 Diagnostic principles
Based on the history of occupational exposure, onset during the exposure period, special clinical manifestations, course of disease, dynamic observation; refer to the investigation of the working environment, etc., comprehensive analysis, exclude non-occupational melanosis, exclude other pigmented skin diseases and secondary pigmentation diseases, and then make a diagnosis.
3 Diagnostic criteria
This disease is a progressive and chronic process, showing skin pigmentation mainly in exposed areas, and in severe cases, it spreads all over the body. It may be accompanied by itching and mild fatigue. Those who meet the following conditions can be diagnosed: 3.1 Before or in the early stage of pigmentation, there are often different degrees of erythema and itching. When the pigmentation is more obvious, these symptoms will be alleviated or disappear.
3.2 The lesions are mostly reticular or plaque (dot) shaped. Some can merge into diffuse patches with unclear boundaries; some present small flakes of pigmentation centered on pores. A few can see capillary dilation and mild epidermal atrophy. 3.3 The color is gray-black, brown-black, purple-black, etc. of varying shades, and the surface of the pigmented area often has a dirty appearance. 3.4 The pigmented areas are mainly exposed areas such as the face and neck, and can occur on the trunk, limbs or distributed all over the body. 3.5 It may be accompanied by mild fatigue, dizziness, loss of appetite and other systemic symptoms. Principles of treatment
4.1 Principles of treatment
Avoid continued contact with pathogens and provide symptomatic treatment. 4.2 Other treatments
4.2.1 Occupational melanosis generally does not affect the ability to work. 4.2.2 Occupational melanosis generally subsides slowly after cessation of contact, and may relapse after resuming contact. Therefore, after diagnosis, the worker should change the type of work to avoid continued contact with pathogens, and may be transferred away from the disease environment if necessary. 5 Instructions for the correct use of this standard
See Appendix A (Informative Appendix).
A.1 Scope of application of this standard
Appendix A
(Informative Appendix)
Instructions for the correct use of this standard
This standard is only applicable to the diagnosis and treatment of occupational melanosis caused by various external factors, and is not applicable to non-occupational melanosis and other pigmentation
2 Skin melanosis is caused by complex external and internal factors. Different patients have different internal and external factors. The several pathogenic substances listed in this standard are the common external factors of occupational melanosis in China. In addition, if it can be confirmed that the onset of the disease has an obvious causal relationship with a certain occupational exposure to poisons, a diagnosis can be given. A.3 When diagnosing occupational melanosis, non-occupational melanosis and secondary pigmentation diseases should be excluded, and attention should be paid to the differentiation from chloasma, lichen planus, pigmented urticaria, multiple macular pigmentation, Addison's disease, hemochromatosis, etc. A.4 The diagnosis of occupational melanosis mainly depends on occupational history and special clinical manifestations. There is currently no specific laboratory diagnostic indicator. The change of -SH in serum can be used as a reference, but it cannot be used as a basis for diagnosis. Histopathological examination is helpful for differentiation from certain pigmented skin diseases such as hemochromatosis, lichen planus, and pigmented urticaria. Biopsy can be performed if necessary.
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