Some standard content:
Chemical Industry Standard of the People's Republic of China
HG/T2354—92
Thin layer chromatography silica gel
Published on August 10, 1992
Ministry of Chemical Industry of the People's Republic of China
Implementation on May 1, 1993
WChemical Industry Standard of the People's Republic of China
Chromatography silica gel
1 Subject content and scope of application
HG/T2354—92
This standard specifies the technical requirements, test methods, inspection rules, and marking, packaging, transportation and storage of thin layer chromatography silica gel. This standard applies to thin layer chromatography silica gel. This product is used as a thin layer chromatography adsorbent in the separation, purification and analysis of organic compounds. Molecular formula: SiO2·nH20
2 Reference standards
Packaging, storage and transportation pictorial symbols
Preparation of standard solutions for titration analysis (volume analysis) of chemical reagents GB601
GB602 Preparation of standard solutions for determination of impurities in chemical reagents GB603 Preparation of preparations and products used in test methods for chemical reagents GB3049 General method for determination of iron content in chemical products O-phenanthroline spectrophotometry 3 Product classification
Thin layer chromatography silica gel includes four types:
aH type: does not contain gypsum and other organic binders. b. HF26 type: does not contain gypsum and other organic binders, contains a fluorescent indicator, and can show yellow-green fluorescence under ultraviolet light of 254nm wavelength.
G type: contains gypsum (calcium sulfate hemihydrate) used as a binder. c.
GF264 type: contains gypsum and a fluorescent indicator. It can show yellow-green fluorescence under ultraviolet light of 254nm wavelength. 4 Technical requirements
4.1 Appearance: white uniform powder.
4.2 Thin layer chromatography silica gel should meet the requirements in the following table. Approved by the Ministry of Chemical Industry of the People's Republic of China on August 10, 1992 and implemented on May 1, 1993
Indicator items
Gypsum (CaSO)
No. H20), %
Chloride (as Cl) %
Iron (Fe) %
pH (100g/L water suspension injection
Sieve residue ( W=38μm）%
Activity\
Superior product
HG/T2354—92
Superior product
Superior product
First-class product
Superior product
12.0~14.012.0~14.012.0~14.012.0~14.00.02
6. 7~7. 06. 0~7. 06. 7~7. 06. 0~7. 040
Three colors separatedThree colors separatedThree colors separatedThree colors separatedNote: 1) The "three colors" in the table refer to dimethyl yellow, Sudan red and indigo. 5 Test methods
Three-color separation
Three-color separation
Three-color separation
Three-color separation
The reagents and water used in this standard, unless otherwise specified, refer to analytical reagents and distilled water or water of corresponding purity. The standard solutions, impurity standard solutions, preparations and products required in the test, unless otherwise specified, shall be prepared in accordance with the provisions of GB601, GB602 and GB603.
5.1 Determination of gypsum content
5.1.1 Summary of the method
In an alkaline medium, calcium red is used as an indicator and the calcium ions in the sample are titrated with EDTA standard titration solution. 5.1.2 Reagents and materials
5.1.2.1 Sodium hydroxide (GB629): 400g/L solution; 5.1.2.2 Hydrochloric acid (GB622): 1+3 solution; 5.1.2.3 Silver nitrate (GB670): 10g/L solution; 5.1.2.4 Disodium ethylenediaminetetraacetic acid (EDTA) (GB1401): c (EDTA) about 0.5mol/L standard titration solution; 5.1.2.5 Calcium red: weigh 0.5g calcium reagent carboxylic acid sodium salt and grind it evenly with 50g sodium chloride. 5.1.3 Instruments and equipment
Microburette: graduation value 0.02mL;
5.1.3.2 Acid-resistant filter funnel: filter plate pore size is 5~15μm. 5.1.4 Analysis steps
Weigh about 0.25g of sample, accurate to 0.0002g, and place in a 250mL ground-mouth conical flask. Add 3mL of hydrochloric acid to moisten, then add 20-30mL of water, stir on a magnetic stirrer for about 30min, and filter with an acid-resistant filter funnel. Wash with water until there is no chloride ion (check with silver nitrate solution). Collect the filtrate and washings in a clean suction flask and control the volume to about 100mL. First, add about 3.5mL of EDTA standard titration solution, then add 4mL of sodium hydroxide solution and 0.1g of calcium red. After shaking well, continue to titrate with EDTA standard titration solution until the solution color changes from purple-red to pure blue, which is the end point. Perform a blank test at the same time.
5.1.5 Expression of analytical results
The content of gypsum (CaSO4,·-H2O) (X) expressed as mass percentage is calculated according to formula (1): 2
W.bzsoso.coIHG/T2354-92
X, = (-V): × 0.145 1 × 100m ...
Gypsum (CasO4·
5.1.6 Allowable difference
The arithmetic mean of the parallel determination results is taken as the determination result; the absolute difference of the parallel determination results shall not exceed 0.3%. 5.2 Determination of chloride content
5.2.1 Method summary
In an acidic medium, the chloride ions in the sample react with silver nitrate to form silver chloride, and its turbidity is compared with that of the chloride standard solution treated in the same way.
5.2.2 Reagents and materials
5.2.2.1 Nitric acid (GB626): 1+1 solution; 5.2.2.2 Silver nitrate (GB670): 17g/L solution; 5.2.2.3 Chloride Standard solution: 0.100mgCl/mL. 5.2.3 Analysis steps
Weigh 5.00±0.01g of sample, place it in a 250mL conical flask, add 100mL of water, stir, and heat to boil for 5min. After cooling, transfer all into a 100mL volumetric flask, dilute to the scale with water, and shake well. Then dry filter, use a pipette to transfer 10mL of filtrate, place it in a 50mL colorimetric tube, add 2mL of nitric acid and 1mL of silver nitrate, dilute to the scale with water, and shake. Let it stand for 10min, and the turbidity should not be greater than the standard.
The standard is to take 1.00mL of chloride standard solution and bury it at the same time as the test solution. 5.3 Determination of iron content||tt ||5.3.1 Summary of the method
Same as Article 2 of GB3049.
5.3.2 Reagents and materials
Provisions of Article 3 of GB3049 and
5.3.2.1 Hydrochloric acid (GB622): 1+7 solution. 5.3.3 Instruments and equipment
5.3.3.1 Spectrophotometer with a 3cm thick absorption cell. 5.3.4 Analysis steps
5.3.4.1 Preparation of test solution
Weigh about 7g (superior product) or 5g (first-class product) of the sample, accurate to 0.01g, and place in a clean and dry 250mL conical flask. Use a pipette to add 100mL of hydrochloric acid solution (5.3.2.1), install the reflux condenser, heat in a boiling water bath for about 30 minutes, perform dry filtration, and collect the filtrate for later use.
5.3.4.2 Drawing of the working curve
Use a 3cm absorption cell and proceed in accordance with Article 5.3 of GB3049. 5.3.4.3 Determination
Use a pipette to transfer 10mL of the test solution and 10mL of hydrochloric acid solution (5.3.2.1) (blank test solution) into 100mL beakers respectively, and proceed in accordance with Article 5.4 of GB3049 starting from "If necessary, add water to 60mL." until the absorbance of the solution 3
is measured.
5.3.5 Expression of analysis results
HG/T2354-92
The iron (Fe) content (w2) expressed as mass percentage is calculated according to formula (2): ×100=m-mo
(m-mo)×10-
m×100
Wherein: m1——iron content found from the working curve according to the measured absorbance of the test solution, mg; mo——iron content found from the working curve according to the measured absorbance of the reagent blank solution, mg; m——sample mass, g.
5.3.6 Allowable differencebZxz.net
The arithmetic mean of the parallel determination results is taken as the determination result; the absolute difference of the parallel determination results shall not exceed 0.002%. 5.4 Determination of pH
5.4.1 Summary of method
The pH value of the test solution is determined by an acidometer equipped with a glass measuring electrode and a saturated calomel reference electrode. 5.4.2 Reagents and materials
5.4.2.1 Water without carbon dioxide.
5.4.3 Instruments and equipment
5.4.3.1 Acidity meter: graduation value 0.02 pH unit. 5.4.4 Analysis steps
Weigh 10.00±0.01g of sample, place it in a 150mL beaker, and add 100mL of water without carbon dioxide. After stirring on a magnetic stirrer for 5 minutes, take the upper water suspension by decantation method and determine its pH value with an acidity meter. 5.4.5 Allowable difference
Take the arithmetic mean of the parallel determination results as the determination result; the absolute difference of the parallel determination results shall not exceed 0.1pH. 5.5 Determination of sieve residue
5.5.1 Instruments and equipment
5.5.1.1 Test sieve (GB6003): R40/3 series, W=38μm. 5.5.2 Analysis steps
Weigh about 10g of sample, accurate to 0.1g, and place it in the test sieve. Gently brush the sample with a brush and shake the sieve continuously by hand. Brush and sieve in this way. After sieving for about 30 minutes, weigh the mass of the sieve residue to an accuracy of 0.01g. 5.5.3 Expression of analysis results
The sieve residue w3 expressed as a mass percentage is calculated according to formula (3): Ws
Where: m1——mass of sieve residue, g; m——mass of sample, g.
5.5.4 Allowable difference
ml×100
Take the arithmetic mean of the parallel determination results as the determination result: the absolute difference of the parallel determination results shall not exceed 2.0%5.6 Determination of activity
5.6.1 Summary of method
Make the sample into a thin layer plate, drop the mixed solution of dimethyl yellow, Sudan red and indigo on it, and place it in benzene for development. The yellow, red and blue colors are clearly separated and qualified.
5.6.2 Reagents and materials
5.6.2. 1 Benzene (GB 690).
HG/T2354—92
5.6.2.2 Three-color mixed solution: Weigh 0.0100±0.0002g of dimethyl yellow, Sudan red and indigo respectively, place in a 150mL beaker, add appropriate amount of benzene to dissolve, transfer all into a 100mL volumetric flask, dilute to scale with benzene, and shake well. 5.6.3 Instruments and equipment
5.6.3.1 Plate spreader (see Figure 1);
Applicator (see Figure 2);
Chromatography cylinder (see Figure 3): Glass cylinder with cover, equipped with glass stand; 5.6.3.4
Glass plate: 5cm×20cm;
Micro-injector: 25μL.
Figure 1 Plate spreader
Figure 2 Coating device
.bzsoso：com5.6.4 Analysis steps
5.6.4.1 Preparation of thin layer plates
HG/T2354—92
Figure 3 Chromatography cylinder
Place three clean and dry glass plates on the plate spreader. Weigh 5.0±0.1g of the sample, place it in a 150mL beaker, and add 14mL of water. Pour it onto the glass plate immediately after stirring, and spread it evenly with a coating device to form a thin layer of silica gel slurry with a thickness of 0.2-0.3mm on the glass plate. After drying in the air, dry it at 105-110℃ for half an hour and place it in a desiccator for use. 5.6.4.2 Spotting and developing
Use a microinjector to inject 40μL of the three-color mixture at a distance of 2.5cm from the bottom edge of the thin layer plate, and then place the plate in the chromatography cylinder. The angle between the thin layer plate and the horizontal plane is about 25, and the liquid surface of the benzene in the chromatography cylinder is 0.51.0cm away from the spotting point of the thin layer plate. Cover the lid. When the development height is 10cm (superior product) or 15cm (first-class product), take out the plate and dry it naturally in the air. 5.6.4.3 Judgment of chromatographic spots
The yellow, red and blue spots formed on the thin layer chromatography plate should be clearly separated, the indigo spot is close to the origin, the dimethyl yellow spot is above the chromatogram, and the Sudan red spot is between the two. The blue and yellow spots are relatively smooth, and the red spot has a little tail. 6 Inspection rules
6.1 Thin layer chromatography silica gel should be inspected by the quality supervision and inspection department of the manufacturer in accordance with the provisions of this standard. The manufacturer shall ensure that all thin layer chromatography silica gel shipped out of the factory meets the requirements of this standard. Each batch of products shipped out of the factory shall be accompanied by a quality certificate. The contents include: manufacturer name, product name, grade, batch number, net weight, production date, proof that the product quality meets this standard and the number of this standard. 6.2 The user has the right to inspect and accept the thin layer chromatography silica gel received in accordance with the provisions of this standard. The inspection and acceptance shall be carried out within 15 days from the date of arrival of the goods.
6.3 The weight of each batch of products shall not exceed 300kg. 6.4 The number of sampling units shall be determined by 3% of the total number of bottles in each batch, and the sample in each bottle shall not be less than 50g; for small batches, the number of sampling units shall not be less than 3 bottles, and the sample in each bottle shall not be less than 300g. Mix the samples, reduce them to about 200g by quartering method, and pack them in two clean, dry wide-mouth bottles with ground stoppers, and seal them. Stick labels on the bottles, indicating: manufacturer name, product name, grade, batch number, sampling date and name of the sampler. One bottle is used for inspection, and the other bottle is kept for three months for future reference. 6.5 If one of the indicators in the inspection results does not meet the requirements of this standard, a sample should be taken from the double amount of packaging for verification. If one of the indicators in the verification results does not meet the requirements of this standard, the entire batch of products cannot be accepted. 6.6 When the supply and demand parties have objections to the product quality, they should handle it in accordance with the provisions of the "Interim Measures for National Product Quality Arbitration Inspection". 6
W.bzsosO.cO7 Marking, packaging, transportation and purchase and storage
HG/T2354-92
7.1 Thin layer chromatography silica gel is packaged in white polyethylene plastic bottles with inner caps. Labels are attached to the bottles, indicating: manufacturer name, product name, specifications, grade, net weight, batch number or production date, trademark and this standard number. The net weight of each bottle is 500g. 7.2 Thin layer chromatography silica gel is packaged in corrugated boxes, with 10 bottles per box. The cartons should be clearly marked with: manufacturer name, product name, specification, grade, batch number or production date, trademark, standard number and the "wet-afraid" mark specified in GB191. 7.3 Thin layer chromatography silica gel should be strictly protected from moisture during storage and transportation, and the packaging box should be kept intact. Additional notes:
This standard was proposed by the Science and Technology Department of the Ministry of Chemical Industry of the People's Republic of China. This standard is technically managed by the Tianjin Chemical Research Institute of the Ministry of Chemical Industry. This standard was drafted by Qingdao Ocean Chemical Plant and the Tianjin Chemical Research Institute of the Ministry of Chemical Industry. The main drafters of this standard are Zhou Zhengshou, Xing Yufen and Chen Guanyuan. This standard refers to the British Pharmacopoeia (1988 edition). 7
W.5.1.1 Test sieve (GB6003): R40/3 series, W=38μm. 5.5.2 Analysis steps
Weigh about 10g of sample, accurate to 0.1g, and place it in the test sieve. Gently brush the sample with a brush and shake the sieve continuously by hand. Brush and sieve in this way. After sieving for about 30 minutes, weigh the mass of the sieve residue, accurate to 0.01g. 5.5.3 Expression of analysis results
The sieve residue w3 expressed as mass percentage is calculated according to formula (3): Ws
Where: m1——mass of sieve residue, g; m——mass of sample, g.
5.5.4 Allowable difference
ml×100
Take the arithmetic mean of the parallel determination results as the determination result: the absolute difference of the parallel determination results shall not exceed 2.0%5.6 Determination of activity
5.6.1 Summary of method
Make the sample into a thin layer plate, drop the mixed solution of dimethyl yellow, Sudan red and indigo on it, and place it in benzene for development. The yellow, red and blue colors are clearly separated and qualified.
5.6.2 Reagents and materials
5.6.2. 1 Benzene (GB 690).
HG/T2354—92
5.6.2.2 Three-color mixed solution: Weigh 0.0100±0.0002g of dimethyl yellow, Sudan red and indigo respectively, place in a 150mL beaker, add appropriate amount of benzene to dissolve, transfer all into a 100mL volumetric flask, dilute to scale with benzene, and shake well. 5.6.3 Instruments and equipment
5.6.3.1 Plate spreader (see Figure 1);
Applicator (see Figure 2);
Chromatography cylinder (see Figure 3): Glass cylinder with cover, equipped with glass stand; 5.6.3.4
Glass plate: 5cm×20cm;
Micro-injector: 25μL.
Figure 1 Plate spreader
Figure 2 Coating device
.bzsoso：com5.6.4 Analysis steps
5.6.4.1 Preparation of thin layer plates
HG/T2354—92
Figure 3 Chromatography cylinder
Place three clean and dry glass plates on the plate spreader. Weigh 5.0±0.1g of the sample, place it in a 150mL beaker, and add 14mL of water. Pour it onto the glass plate immediately after stirring, and spread it evenly with a coating device to form a thin layer of silica gel slurry with a thickness of 0.2-0.3mm on the glass plate. After drying in the air, dry it at 105-110℃ for half an hour and place it in a desiccator for use. 5.6.4.2 Spotting and developing
Use a microinjector to inject 40μL of the three-color mixture at a distance of 2.5cm from the bottom edge of the thin layer plate, and then place the plate in the chromatography cylinder. The angle between the thin layer plate and the horizontal plane is about 25, and the liquid surface of the benzene in the chromatography cylinder is 0.51.0cm away from the spotting point of the thin layer plate. Cover the lid. When the development height is 10cm (superior product) or 15cm (first-class product), take out the plate and dry it naturally in the air. 5.6.4.3 Judgment of chromatographic spots
The yellow, red and blue spots formed on the thin layer chromatography plate should be clearly separated, the indigo spot is close to the origin, the dimethyl yellow spot is above the chromatogram, and the Sudan red spot is between the two. The blue and yellow spots are relatively smooth, and the red spot has a little tail. 6 Inspection rules
6.1 Thin layer chromatography silica gel should be inspected by the quality supervision and inspection department of the manufacturer in accordance with the provisions of this standard. The manufacturer shall ensure that all thin layer chromatography silica gel shipped out of the factory meets the requirements of this standard. Each batch of products shipped out of the factory shall be accompanied by a quality certificate. The contents include: manufacturer name, product name, grade, batch number, net weight, production date, proof that the product quality meets this standard and the number of this standard. 6.2 The user has the right to inspect and accept the thin layer chromatography silica gel received in accordance with the provisions of this standard. The inspection and acceptance shall be carried out within 15 days from the date of arrival of the goods.
6.3 The weight of each batch of products shall not exceed 300kg. 6.4 The number of sampling units shall be determined by 3% of the total number of bottles in each batch, and the sample in each bottle shall not be less than 50g; for small batches, the number of sampling units shall not be less than 3 bottles, and the sample in each bottle shall not be less than 300g. Mix the samples, reduce them to about 200g by quartering, and pack them in two clean, dry wide-mouth bottles with ground stoppers, and seal them. Label the bottles with the following: manufacturer name, product name, grade, batch number, sampling date and name of the sampler. One bottle is used for inspection, and the other bottle is kept for three months for future reference. 6.5 If one of the indicators in the inspection results does not meet the requirements of this standard, a sample should be taken from the double amount of packaging for verification. If one of the indicators in the verification results does not meet the requirements of this standard, the entire batch of products cannot be accepted. 6.6 When the supply and demand parties have objections to the product quality, they should handle it in accordance with the provisions of the "Interim Measures for National Product Quality Arbitration Inspection". 6
W.bzsosO.cO7 Marking, packaging, transportation and purchase and storage
HG/T2354-92
7.1 Thin layer chromatography silica gel is packaged in white polyethylene plastic bottles with inner caps. Labels are attached to the bottles, indicating: manufacturer name, product name, specifications, grade, net weight, batch number or production date, trademark and this standard number. The net weight of each bottle is 500g. 7.2 Thin layer chromatography silica gel is packaged in corrugated boxes, with 10 bottles per box. The cartons should be clearly marked with: manufacturer name, product name, specification, grade, batch number or production date, trademark, this standard number and the "wet-afraid" mark specified in GB191. 7.3 Thin layer chromatography silica gel should be strictly protected from moisture during storage and transportation, and the packaging box should be kept intact. Additional notes:
This standard was proposed by the Science and Technology Department of the Ministry of Chemical Industry of the People's Republic of China. This standard is technically managed by the Tianjin Chemical Research Institute of the Ministry of Chemical Industry. This standard was drafted by Qingdao Ocean Chemical Plant and the Tianjin Chemical Research Institute of the Ministry of Chemical Industry. The main drafters of this standard are Zhou Zhengshou, Xing Yufen and Chen Guanyuan. This standard refers to the British Pharmacopoeia (1988 edition). 7
W.5.1.1 Test sieve (GB6003): R40/3 series, W=38μm. 5.5.2 Analysis steps
Weigh about 10g of sample, accurate to 0.1g, and place it in the test sieve. Gently brush the sample with a brush and shake the sieve continuously by hand. Brush and sieve in this way. After sieving for about 30 minutes, weigh the mass of the sieve residue, accurate to 0.01g. 5.5.3 Expression of analysis results
The sieve residue w3 expressed as mass percentage is calculated according to formula (3): Ws
Where: m1——mass of sieve residue, g; m——mass of sample, g.
5.5.4 Allowable difference
ml×100
Take the arithmetic mean of the parallel determination results as the determination result: the absolute difference of the parallel determination results shall not exceed 2.0%5.6 Determination of activity
5.6.1 Summary of method
Make the sample into a thin layer plate, drop the mixed solution of dimethyl yellow, Sudan red and indigo on it, and place it in benzene for development. The yellow, red and blue colors are clearly separated and qualified.
5.6.2 Reagents and materials
5.6.2. 1 Benzene (GB 690).
HG/T2354—92
5.6.2.2 Three-color mixed solution: Weigh 0.0100±0.0002g of dimethyl yellow, Sudan red and indigo respectively, place in a 150mL beaker, add appropriate amount of benzene to dissolve, transfer all into a 100mL volumetric flask, dilute to scale with benzene, and shake well. 5.6.3 Instruments and equipment
5.6.3.1 Plate spreader (see Figure 1);
Applicator (see Figure 2);
Chromatography cylinder (see Figure 3): Glass cylinder with cover, equipped with glass stand; 5.6.3.4
Glass plate: 5cm×20cm;
Micro-injector: 25μL.
Figure 1 Plate spreader
Figure 2 Coating device
.bzsoso：com5.6.4 Analysis steps
5.6.4.1 Preparation of thin layer plates
HG/T2354—92
Figure 3 Chromatography cylinder
Place three clean and dry glass plates on the plate spreader. Weigh 5.0±0.1g of the sample, place it in a 150mL beaker, and add 14mL of water. Pour it onto the glass plate immediately after stirring, and spread it evenly with a coating device to form a thin layer of silica gel slurry with a thickness of 0.2-0.3mm on the glass plate. After drying in the air, dry it at 105-110℃ for half an hour and place it in a desiccator for use. 5.6.4.2 Spotting and developing
Use a microinjector to inject 40μL of the three-color mixture at a distance of 2.5cm from the bottom edge of the thin layer plate, and then place the plate in the chromatography cylinder. The angle between the thin layer plate and the horizontal plane is about 25, and the liquid surface of the benzene in the chromatography cylinder is 0.51.0cm away from the spotting point of the thin layer plate. Cover the lid. When the development height is 10cm (superior product) or 15cm (first-class product), take out the plate and dry it naturally in the air. 5.6.4.3 Judgment of chromatographic spots
The yellow, red and blue spots formed on the thin layer chromatography plate should be clearly separated, the indigo spot is close to the origin, the dimethyl yellow spot is above the chromatogram, and the Sudan red spot is between the two. The blue and yellow spots are relatively smooth, and the red spot has a little tail. 6 Inspection rules
6.1 Thin layer chromatography silica gel should be inspected by the quality supervision and inspection department of the manufacturer in accordance with the provisions of this standard. The manufacturer shall ensure that all thin layer chromatography silica gel shipped out of the factory meets the requirements of this standard. Each batch of products shipped out of the factory shall be accompanied by a quality certificate. The contents include: manufacturer name, product name, grade, batch number, net weight, production date, proof that the product quality meets this standard and the number of this standard. 6.2 The user has the right to inspect and accept the thin layer chromatography silica gel received in accordance with the provisions of this standard. The inspection and acceptance shall be carried out within 15 days from the date of arrival of the goods.
6.3 The weight of each batch of products shall not exceed 300kg. 6.4 The number of sampling units shall be determined by 3% of the total number of bottles in each batch, and the sample in each bottle shall not be less than 50g; for small batches, the number of sampling units shall not be less than 3 bottles, and the sample in each bottle shall not be less than 300g. Mix the samples, reduce them to about 200g by quartering method, and pack them in two clean, dry wide-mouth bottles with ground stoppers, and seal them. Stick labels on the bottles, indicating: manufacturer name, product name, grade, batch number, sampling date and name of the sampler. One bottle is used for inspection, and the other bottle is kept for three months for future reference. 6.5 If one of the indicators in the inspection results does not meet the requirements of this standard, a sample should be taken from the double amount of packaging for verification. If one of the indicators in the verification results does not meet the requirements of this standard, the entire batch of products cannot be accepted. 6.6 When the supply and demand parties have objections to the product quality, they should handle it in accordance with the provisions of the "Interim Measures for National Product Quality Arbitration Inspection". 6
W.bzsosO.cO7 Marking, packaging, transportation and purchase and storage
HG/T2354-92
7.1 Thin layer chromatography silica gel is packaged in white polyethylene plastic bottles with inner caps. Labels are attached to the bottles, indicating: manufacturer name, product name, specifications, grade, net weight, batch number or production date, trademark and this standard number. The net weight of each bottle is 500g. 7.2 Thin layer chromatography silica gel is packaged in corrugated boxes, with 10 bottles per box. The cartons should be clearly marked with: manufacturer name, product name, specification, grade, batch number or production date, trademark, this standard number and the "wet-afraid" mark specified in GB191. 7.3 Thin layer chromatography silica gel should be strictly protected from moisture during storage and transportation, and the packaging box should be kept intact. Additional notes:
This standard was proposed by the Science and Technology Department of the Ministry of Chemical Industry of the People's Republic of China. This standard is technically managed by the Tianjin Chemical Research Institute of the Ministry of Chemical Industry. This standard was drafted by Qingdao Ocean Chemical Plant and the Tianjin Chemical Research Institute of the Ministry of Chemical Industry. The main drafters of this standard are Zhou Zhengshou, Xing Yufen and Chen Guanyuan. This standard refers to the British Pharmacopoeia (1988 edition). 7
W.3 Judgment of chromatographic spots
The yellow, red and blue spots formed on the thin layer chromatography plate should be clearly separated, the indigo spots are close to the origin, the dimethyl yellow spots are above the chromatogram, and the Sudan red spots are between the two. The blue and yellow spots are relatively smooth, and the red spots have a little tail. 6 Inspection rules
6.1 Thin layer chromatography silica gel should be inspected by the quality supervision and inspection department of the manufacturer in accordance with the provisions of this standard. The manufacturer should ensure that all thin layer chromatography silica gel shipped from the factory meets the requirements of this standard. Each batch of products shipped from the factory should be accompanied by a quality certificate. The content includes: manufacturer name, product name, grade, batch number, net weight, production date, product quality certificate of compliance with this standard and this standard number. 6.2 The user has the right to accept the thin layer chromatography silica gel received in accordance with the provisions of this standard. The acceptance should be carried out within 15 days from the date of arrival.
6.3 The weight of each batch of products shall not exceed 300kg. 6.4 The number of sampling units shall be determined by 3% of the total number of bottles in each batch, and the sample in each bottle shall not be less than 50g; in small batches, the number of sampling units shall not be less than 3 bottles, and the sample in each bottle shall not be less than 300g. Mix the samples, reduce them to about 200g by quartering, and pack them in two clean, dry wide-mouth bottles with ground stoppers, and seal them. Label the bottles with: manufacturer name, product name, grade, batch number, sampling date and sampler name. One bottle is used for inspection, and the other is kept for three months for future reference. 6.5 If one indicator in the inspection result does not meet the requirements of this standard. Sampling should be re-checked from twice the amount of packaging. If the inspection result shows that one indicator does not meet the requirements of this standard, the entire batch of products cannot be accepted. 6.6 When the supply and demand parties have objections to the product quality, they should handle it in accordance with the provisions of the "Interim Measures for National Product Quality Arbitration Inspection". 6
W.bzsosO.cO7 Marking, packaging, transportation and purchase and storage
HG/T2354—92
7.1 Thin layer chromatography silica gel is packaged in white polyethylene plastic bottles with inner caps. Labels are affixed to the bottles, indicating: manufacturer name, product name, specifications, grade, net weight, batch number or production date, trademark and this standard number. Net weight of each bottle is 500g. 7.2 Thin layer chromatography silica gel is packaged in corrugated paper boxes, with 10 bottles per box. The carton should have firm and clear markings indicating: manufacturer name, product name, specifications, grade, batch number or production date, trademark, this standard number and the "wet-afraid" mark specified in GB191. 7.3 Thin layer chromatography silica gel should be strictly protected from moisture during storage and transportation, and the packaging box should be kept intact. Additional remarks:
This standard is proposed by the Science and Technology Department of the Ministry of Chemical Industry of the People's Republic of China. This standard is technically managed by the Tianjin Chemical Research Institute of the Ministry of Chemical Industry. This standard was drafted by Qingdao Ocean Chemical Plant and Tianjin Chemical Research Institute of the Ministry of Chemical Industry. The main drafters of this standard are Zhou Zhengshou, Xing Yufen and Chen Guanyuan. This standard is based on the British Pharmacopoeia (1988 edition). 7
W.3 Judgment of chromatographic spots
The yellow, red and blue spots formed on the thin layer chromatography plate should be clearly separated, the indigo spots are close to the origin, the dimethyl yellow spots are above the chromatogram, and the Sudan red spots are between the two. The blue and yellow spots are relatively smooth, and the red spots have a little tail. 6 Inspection rules
6.1 Thin layer chromatography silica gel should be inspected by the quality supervision and inspection department of the manufacturer in accordance with the provisions of this standard. The manufacturer should ensure that all thin layer chromatography silica gel shipped from the factory meets the requirements of this standard. Each batch of products shipped from the factory should be accompanied by a quality certificate. The content includes: manufacturer name, product name, grade, batch number, net weight, production date, product quality certificate of compliance with this standard and this standard number. 6.2 The user has the right to accept the thin layer chromatography silica gel received in accordance with the provisions of this standard. The acceptance should be carried out within 15 days from the date of arrival.
6.3 The weight of each batch of products shall not exceed 300kg. 6.4 The number of sampling units shall be determined by 3% of the total number of bottles in each batch, and the sample in each bottle shall not be less than 50g; in small batches, the number of sampling units shall not be less than 3 bottles, and the sample in each bottle shall not be less than 300g. Mix the samples, reduce them to about 200g by quartering, and pack them in two clean, dry wide-mouth bottles with ground stoppers, and seal them. Label the bottles with: manufacturer name, product name, grade, batch number, sampling date and sampler name. One bottle is used for inspection, and the other is kept for three months for future reference. 6.5 If one indicator in the inspection result does not meet the requirements of this standard. Sampling should be re-checked from twice the amount of packaging. If the inspection result shows that one indicator does not meet the requirements of this standard, the entire batch of products cannot be accepted. 6.6 When the supply and demand parties have objections to the product quality, they should handle it in accordance with the provisions of the "Interim Measures for National Product Quality Arbitration Inspection". 6
W.bzsosO.cO7 Marking, packaging, transportation and purchase and storage
HG/T2354—92
7.1 Thin layer chromatography silica gel is packaged in white polyethylene plastic bottles with inner caps. Labels are affixed to the bottles, indicating: manufacturer name, product name, specifications, grade, net weight, batch number or production date, trademark and this standard number. Net weight of each bottle is 500g. 7.2 Thin layer chromatography silica gel is packaged in corrugated paper boxes, with 10 bottles per box. The carton should have firm and clear markings indicating: manufacturer name, product name, specifications, grade, batch number or production date, trademark, this standard number and the "wet-afraid" mark specified in GB191. 7.3 Thin layer chromatography silica gel should be strictly protected from moisture during storage and transportation, and the packaging box should be kept intact. Additional remarks:
This standard is proposed by the Science and Technology Department of the Ministry of Chemical Industry of the People's Republic of China. This standard is technically managed by the Tianjin Chemical Research Institute of the Ministry of Chemical Industry. This standard was drafted by Qingdao Ocean Chemical Plant and Tianjin Chemical Research Institute of the Ministry of Chemical Industry. The main drafters of this standard are Zhou Zhengshou, Xing Yufen and Chen Guanyuan. This standard is based on the British Pharmacopoeia (1988 edition). 7
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