Some standard content:
GB 8820—1988
National Standard of the People's Republic of China
Food Additive Zinc Gluconate
Foodadditive-Zincgluconate
GB8820—1988
This standard applies to zinc gluconate obtained by acidifying and reacting with zinc compounds or reacting with gluconolactone as raw material with zinc compounds, which is used as a nutritional enhancer in the food industry. Molecular formula C12H22O14Zn
Structural formula
H, CHH
Molecular weight 455.68 (according to the international atomic weight in 1983) 1 Technical requirements
11 Properties This product is white or off-white granules or crystalline powder, soluble in water and slightly soluble in ethanol. 1.2 This product should meet the requirements of the following table.
Indicator name
Content (in Ci2H2014Zn), %
Water, %
Reducing substances (in C6H120), %
Chloride (in C1), %
Sulfate (in SO), %
Arsenic (in As), %
Lead (in Pb), %
Cadmium (in Cd), %
2 Test method
97.0~102.0
This standard is applicable to the reagents used. Unless otherwise specified, they refer to analytical pure reagents. The water used refers to distilled water or water of corresponding purity. The solution is an aqueous solution. The instruments and equipment are general laboratory equipment. 2.1 Identification
2.1.1 Reagents and solutions
2.1.1.1 Potassium ferrocyanide (GB1273-77) 1-→10 aqueous solution, this solution should be freshly prepared before use. 2.1.12 Dilute hydrochloric acid: Take 234mL hydrochloric acid (GB622-77) and dilute to 1000mL with water, shake well. 2.1.1.3 Glacial acetic acid (GB676-78). Approved by the State Food and Drug Administration on February 22, 1988, implemented on August 1, 1988
GB8820-1988
2.1.1.4 Benzyl hydrazine.
2.1.2 Analysis steps
2.1.2.1 Take a few drops of the aqueous solution (1→20) of this product, add potassium ferrocyanide solution, and a white precipitate will appear, separate, and the precipitate will not dissolve in dilute hydrochloric acid. 2.1.2.2 Take 1.0g of this product and add 10mL of water to dissolve (heat if necessary), take 5mL, add 0.7mL of glacial acetic acid and 1mL of freshly distilled phenylhydrazine, heat on a water bath for 30min, cool, rub the inner wall of the test tube with a glass rod, and crystals will precipitate.
2.2 Determination of zinc gluconate content
2.2.1 Reagents and solutions
2.2.1.1 Ammonia water (GB631-77).
2.2.1.2 Ammonium chloride (GB658-77).
2.2.1.3 Ammonia-ammonium chloride buffer (pH=10): Weigh 5.4g of ammonium chloride, add 20mL of water to dissolve, add 35mL of ammonia water, dilute to 100mL with water, and shake well. 2.2.1.4 Disodium ethylenediaminetetraacetic acid (GB140185): 0.05 mol/L standard solution, prepared and calibrated according to GB601-77 "Standard Solution Preparation Method". 2.2.1.5 Eriochrome Black T.
2.2.1.6 Sodium chloride (GB1266-86). 2.2.1.7 Eriochrome Black T indicator: weigh 0.1g of Eriochrome Black T and add 10g of sodium chloride, grind evenly, and obtain. 2.2.2 Analysis steps
Take about 0.5g of this product, weigh accurately, add 100mL of water, dissolve (heat if necessary), add 5mL of ammonia-ammonium chloride buffer, a little Eriochrome Black T indicator, and titrate with disodium ethylenediaminetetraacetic acid solution until the solution turns blue. Each milliliter of disodium ethylenediaminetetraacetic acid solution (0.05 mol/L) is equivalent to 22.78mg of zinc gluconate.
2.2.3 Calculation of analysis results
M×V×0.02278×20
m×(1-xz)
Wherein: Xi——content of zinc gluconate (in terms of Ci2H2014Zn), %; M—concentration of disodium ethylenediaminetetraacetic acid solution, mol/L; V—amount of disodium ethylenediaminetetraacetic acid solution used, mL; m——sample mass, g;
X2—sample moisture content, %.
2.3 Determination of moisture content
2.3.1 Fischer titration
2.3.1.1 Principle The moisture content is determined based on the principle that iodine and sulfur dioxide can react quantitatively with water in pyridine and methanol solutions. Therefore, the instrument should be dry and able to avoid the intrusion of moisture in the air. The determination operation should be carried out in a dry place.
2.3.1.2 Preparation and calibration of Fischer's reagent Preparation: Weigh 110g of iodine (placed in a sulfuric acid dryer for more than 48 hours), place in a dry stoppered flask, add 160mL of anhydrous pyridine, pay attention to cooling, shake until the iodine is completely dissolved, add 300mL of anhydrous methanol, weigh the weight, cool the flask in an ice bath, pass dry sulfur dioxide until the weight increases by 72g, add anhydrous methanol to make the volume 1000mL, stopper, shake well, and place in the dark for 24 hours. This solution should be kept away from light, sealed, and stored in a cool and dry place, and the concentration should be calibrated before use. Calibration: Take a dry stoppered glass bottle, accurately weigh about 30 mg of double distilled water, add 2~5 mL of anhydrous methanol, and titrate with this solution until the solution changes from light yellow to reddish brown, or use the water perpetual titration method to indicate the end point, and make a blank test. Calculate according to the following formula to get F
The mass of water equivalent to each 1 mL of Fischer test solution, mg; In the formula: F
W—the mass of double distilled water weighed, mg;
A The volume of Fehling test solution consumed in titration, mL; B The volume of Fischer test solution consumed in blank, mL. 2.3.1.3 Apparatus
A ground-mouth stoppered glass bottle (automatic burette) with a burette device is shown in Figure 1: T
1-silica gel desiccant; 2-automatic burette; 3-double-balloon; 4-graduated burette 2. 3.1.4 Analysis steps
Take about 100 mg of fine powder of this product, weigh it accurately, put it in a dry glass bottle with a soft rubber stopper, add 5.0 mL of anhydrous methanol, plug it tightly, and under constant stirring (on a magnetic stirring device), immediately titrate with Fischer's reagent (the injection needle inserted into the glass bottle through the rubber stopper) until the solution changes from light yellow to reddish brown or the end point is indicated by the stop titration method; perform a blank test and calculate according to the following formula to obtain the result. 2.3.1.5 Calculation of analysis results
Wherein: x2
(AA)F
Water content in sample, %;
Volume of Fischer reagent consumed in sample, mL; Volume of Fischer reagent consumed in blank, mL; Mass of water equivalent to 1mL of Fischer reagent, mg; - Mass of sample, mg.
2.3.2 Loss on drying method
2.3.2.1 Instruments and equipment
2.3.2.1.1 Electric oven
2.3.2.1.2 Weighing bottle
2.3.2.2 Determination method
Can be controlled at 105±5℃.
Φ40×25mm.
Approved by the State Food and Drug Administration on February 22, 1988 (3)
Implemented on August 1, 1988
GB8820-1988
Take about 1.0g of the fine powder of this product, place it in a weighing bottle that has been dried to constant weight at 105℃, weigh it accurately, and then dry it in an electric oven at 105℃ to constant weight. Calculate the sample's loss on drying from the lost mass and the sample amount. 2.3.2.3 Calculation of analysis results
m, -m4×100
Where: X3—
Sample loss on drying, %;
Weight of weighing bottle and sample before drying, g;
Weight of weighing bottle and sample after drying, g;
-Weighing bottle mass, g.
2.4 Determination of reducing substances
2.4.1 Reagents and solutions
Copper sulfate (GB66578).
Trisodium citrate (sodium citrate) (HG31298-80). 2.4.1.3
Anhydrous sodium carbonate (GB63986).
2.4.1.4 Glacial acetic acid (GB676-78).
2.4.1.5 Preparation of alkaline copper citrate solution: (4)
Solution A: Weigh 17.3 g of copper sulfate crystals and 115.0 g of sodium citrate, add warm water to dissolve to 200 mL.
Solution B: Weigh 185.0 g of anhydrous sodium carbonate dried at 180°C for 2 h.3g, add water to dissolve into 500mL. Before use, take 50mL of solution B, and slowly add 20mL of solution A under continuous shaking. After cooling, add water to dilute to 100mL.
2.4.1.6 Iodine (GB675-77): 0.1mol/L standard solution is prepared and calibrated according to GB60177. 2.4.1.7 Sodium thiosulfate (GB637-77): 0.1mol/L standard solution is prepared and calibrated according to GB601-77.
2.4.1.8 Starch indicator solution: weigh 0.5g of soluble starch, add 50mL of water and stir well, then slowly pour into 100mL of boiling water, stirring as it is added, continue to boil for 2min, cool, and pour out the supernatant for use. This solution should be freshly prepared before use.
2.4.2 Analysis steps
Weigh about 1.0g of this product, weigh accurately, put it in a 250mL iodine bottle, add 10mL of water (heat if necessary) to dissolve, let it cool, accurately add 25.0mL of alkaline copper citrate solution, cover the bottle mouth with a small surface, carefully and accurately boil for 5 minutes, quickly cool to room temperature, add 25.0mL of 0.6mol/L acetic acid, shake well, accurately add 10.0mL of iodine standard solution, seal, shake well, let it stand for 10 minutes, carefully add 10mL of 3mol/L hydrochloric acid, then add 3.0mL of starch indicator solution, immediately titrate with 0.1mol/L sodium thiosulfate solution until the solution turns bright blue, and correct the titration result with a blank test. Each milliliter of sodium thiosulfate solution (0.1mol/L) is equivalent to 2.7mg of glucose.
2.4.3 Calculation of analysis results
M(V -V,)×0.0027×10
Where: X4-amount of reducing substances in the sample (in terms of C6H120), %M-concentration of sodium thiosulfate standard solution, mol/L; Vi-amount of standard solution consumed by blank during titration, mL; V2-amount of standard solution consumed by sample during titration, mL; Approved by the State Food and Drug Administration on February 22, 1988 (5)
Implementation on August 1, 1988
GB8820-1988
m. —mass of sample, g.
2.5 Determination of chloride
2.5.1 Reagents and solutions
2.5.1.1 Dilute nitric acid: Take 105 mL of nitric acid (GB626-78) and dilute it to 1000 mL with water. 2.5.1.2 Silver nitrate (GB67086): 0.1 mol/L standard solution, prepared and calibrated according to GB601-77.
2.5.1.3 Preparation of sodium chloride standard solution: Prepare and calibrate according to GB602-77 "Preparation Method of Standard Solution of Impurities", and dilute to contain 10μg of C1 per ml when used. 2.5.2 Instruments and equipment: 2 matching Nessler colorimetric tubes. 5.3 Analysis steps: Accurately weigh 0.40g of this product, place it in a 100mL volumetric flask, add 80mL of water to dissolve, then dilute with water to the scale, shake well, accurately draw 10.0mL, place it in a 50mL Nessler colorimetric tube, add 20mL of water and shake well, and add 10mL of dilute nitric acid to obtain the test solution. Take 2mL of sodium chloride standard solution (10μgC1/mL) and place it in another 50mL Nessler colorimetric tube, add 10mL of dilute nitric acid, add water to make 40mL, shake well, and this is the reference solution. Add 1mL of silver nitrate solution to the test solution and the reference solution respectively, dilute to the scale with water, shake well, place in a dark place for 5min, place on a black background, observe and compare from the top of the colorimetric tube downward, the turbidity produced by the test solution shall not be darker than that of the reference. 2.6 Sulfate determination
2.6.1 Reagents and solutions
2.6.1.1 Dilute hydrochloric acid (same as 2.1.1.2).
2.6.1.2 Barium chloride (GB652-78) 25% solution. 2.6.1.3 Sulfate standard solution: Prepare according to GB602-77. Each ml contains 100μg S0. 2.6.2 Instruments and equipment: Nessler colorimetric tube. 2.6.3 Analysis steps: Weigh 0.5g of this product, put it in a 50mL Nessler colorimetric tube, add water to dissolve, add 2mL of dilute hydrochloric acid and shake well, then dilute with water to 40mL, shake well to get the test solution. Take another 2.5mL of sulfate standard solution in another 50mL Nessler colorimetric tube, add 2mL of dilute hydrochloric acid, and then add water to make 40mL to get the reference solution.
Add 5mL of chlorinated sodium solution to the test solution and the reference solution respectively, then dilute with water to the scale, shake well, let it stand for 10min, put it on a black background, observe and compare from the top of the colorimetric tube downward, the turbidity produced by the test solution shall not be darker than that of the reference solution. 2.7 Determination of arsenic
Weigh 2.50g of sample (without digestion or ashing treatment), dissolve in water and make up to 25.0mL for testing, measure 10.0mL (equivalent to 1.0g of original sample), and perform the test according to the second method of GB5009.11-85 "Determination of total arsenic in food".
2.8 Determination of lead
2.8.1 Atomic absorption spectrophotometry
2.8.1.1 Reagents and solutions
Deionized water, high-grade or high-grade pure reagents are required. 2.8.1.1.1 Nitric acid (GB626-78): 6mol/L and 1.0% solution. 2.8.1.1.2 Lead standard solution: Weigh 1.0000g of metallic lead (99.99%) accurately, dissolve it by adding 6mol/L nitric acid in batches, the total amount should not exceed 37mL, transfer it into a 1000mL volumetric flask, dilute it to the mark with water, and each milliliter of this solution is equivalent to 1mg of lead.
2.8.1.1.3 Lead standard working solution: Pipette 10.0mL of lead standard solution into a 100mL volumetric flask, dilute it to the mark with 1.0% nitric acid. Dilute it several times until each milliliter is equivalent to 10μg of lead. Approved by the State Drug Administration on February 22, 1988, implemented on August 1, 1988
GB8820-1988
2.8.1.2 Instruments
2.8.1.2.1 Atomic absorption spectrophotometer. 2.8.1.2.2 All glassware used shall be soaked in 10% to 20% nitric acid for more than 24 hours, rinsed repeatedly with double distilled water, and finally rinsed with deionized water and dried before use. 2.8.1.3 Analysis steps
Accurately weigh 2.5g of this product, dissolve it with 1% nitric acid and make up to 25mL. Take 0, 10, 20, and 40mL of lead standard solution, dilute it with 1% nitric acid and make up to 50mL (0, 2, 4, and 8μg of lead per mL).
Introduce this product solution and each standard solution into the flame for determination. Determination conditions: lamp current 7.5mA, wavelength 283.3nm, slit 1.3nm, air flow 7.5L/min, acetylene flow 1/min, lamp head height 3mm, chlorine lamp background correction (it can also be adjusted to the best conditions according to the instrument model), and draw a standard curve for comparison with the absorbance corresponding to the lead content. bzxZ.net
2.8.1.4 Calculation of analysis results
Wherein: Xs
(A, - A4)×V,×100
mz×1000×1000
Lead content in sample, %;
-Lead content in sample solution for determination, μg/mL;-Lead content in reagent blank solution, μg/mL; V3—Total volume after sample treatment, mL; m7
Sample mass, g.
2.8.2 Colorimetric method
2.8.2.1 Reagents and solutions
: (6)
Perform the dithiol colorimetric method, method 1, in GB5009.12-85 “Determination of lead in food”. 2.8.2.2 Analysis steps
Accurately weigh 2.50 g of sample, add 1% nitric acid to dissolve and dilute to 25.0 mL for testing. Pipette sample solution 10.0mL (equivalent to 1g of the original sample) is placed in a 125mL separatory funnel. Accurately pipette 0, 1, 2, 3, 4, 5mL of lead standard solution (equivalent to 0, 1, 2, 3, 4, 5μg of lead) and place them in 125mL separatory funnels respectively, and add 1% nitric acid solution to each to 20mL. Add 20% ammonium citrate solution 2mL, 205 hydroxylamine hydrochloride solution 1mL and 2 drops of phenol red indicator to the sample solution and lead standard solution respectively, adjust to orange-red with 1:1 ammonia water, and then add 20mL of 10% potassium cyanide solution to each and mix well. Add 10mL of dithiamine solution to each layer, shake vigorously for 1min (about 200 times), let stand to separate, discard the water layer, and use washing liquid (take 5mL of 10% potassium cyanide solution, add water to 500mL, wash 3 to 4 times, 20mL each time, until there is no dithiamine and the chloroform layer is clear red, filter it into a 1cm colorimetric cup through absorbent cotton, adjust the zero point with a 0 tube and measure the absorbance at a wavelength of 510nm, draw a standard curve for comparative quantification. Note: 1) For every 1gKCN equivalent of potassium cyanide waste liquid, 25mL of 10% NazCO solution and 25mL of 30% FeSO4 should be added, and then diluted with water for discharge.
2.8.2.3 Calculation of analysis results
(A, A)×100
×1000×1000
Where: X6 Lead content in sample, %;
As—Lead content in sample digestion solution for determination, ug/mL; Approved by the State Food and Drug Administration on February 22, 1988 (7)
Implemented on August 1, 1988
GB8820—1988
A6 Lead content in reagent blank solution, μg/mL; m8 Sample mass, g;
V4—Total volume of sample digestion solution, mL: Vs—Volume of sample digestion solution for determination, mL. 2.9 Determination of cadmium
2.9.1 Reagents and solutions
Deionized water and high-grade or high-grade reagents are required. 2.9.1.1 Nitric acid (GB626-78): 1:1 and 1% solution. 2.9.1.2 Metal pickaxe powder, spectrally pure.
2.9.1.3 Pickaxe standard solution: Accurately weigh 1.000g of metal pickaxe (99.99%), moisten it with a few drops of water, add 10mL of 1:1 nitric acid to dissolve it, quantitatively transfer it into a 1000mL volumetric flask, dilute it to the mark with water, shake it well, and you will get a concentrated standard solution. Each mL of this solution is equivalent to 1mg. Store in a polyethylene bottle. 2.9.1.4 Pickaxe standard working solution: Pipette 1.0mL of pickaxe standard solution into a 100mL volumetric flask, add 1% nitric acid to the mark, mix it with a spoon, and each mL of this solution is equivalent to 10ug of cadmium. 2.9.2 Instruments
2.9.2.1 Atomic absorption spectrophotometer.
2.9.2.2 All glassware used shall be soaked in 10% to 20% nitric acid for more than 24 hours, rinsed repeatedly with double distilled water, and finally rinsed with deionized water and dried before use. 2.9.3 Analysis steps
Accurately weigh 2.5g of sample, dissolve it with 1% nitric acid and make up to 25mL. Take 0, 1.25, 2.50, 5.00mL of standard working solution, dilute it with 1% nitric acid and make up to 50mL (each mL is equivalent to 0, 0.25, 0.50, 1.00ug of nitric acid). The sample solution and each standard solution are introduced into the flame for measurement. The measurement conditions are: lamp current 6 to 7mA, wavelength 228.8nm, slit 0.15 to 0.2nm, air flow 5L/min, acetylene flow 0.4L/min, lamp head height 1mm, chlorine lamp background correction (it can also be adjusted to the best conditions according to the instrument model), and the standard curve is drawn for comparison with the absorbance corresponding to the concentration of cadmium content. 2.9.4 Calculation of analysis results
(A, - Ag)× V6
mg×1000×1000
Where:
Cadmium content in sample, %;
A—Content in sample solution for determination, μg/mL; Hg content in Ag reagent blank solution, μg/mL; V. Total volume of sample after treatment, mL;
3 Acceptance rules
Sample mass, g.
**** (8)
3.1 This product shall be inspected by the quality inspection department of the manufacturer, and all products leaving the factory shall meet the requirements of this standard.
3.2 The user may verify the quality of the received products in accordance with the inspection rules and test methods specified in this standard.
3.3 The weight of each batch shall not exceed the daily output of the manufacturer. 3.4 Sampling method: 2% of the number of bags in each batch shall be used to select samples. The small batch shall not be less than 3 bags. From the selected number of bags, use the sampling tool to reach into 3/4 of each bag and take out samples of not less than 100g. The taken samples shall be quickly mixed, divided into quarters, and placed in a clean and dry wide-mouth bottle with a ground mouth (the capacity shall not be less than 250mL). The bottle shall be labeled with the name of the manufacturer, production date, product name, batch number and sampling date, and sent to the laboratory for timely analysis.
3:5 If one of the test results does not meet the standard, the sample shall be doubled for testing. If one of the results of the re-test still does not meet the standard, the whole batch shall be determined as unqualified. 3.6 If the supply and demand parties have disputes over product quality and need arbitration, the two parties may negotiate the arbitration unit and conduct it according to the methods and acceptance rules specified in this standard. 4 Marking, packaging, transportation and storage
4.1 The packaging materials of zinc gluconate must meet the hygiene standards and requirements. The packaged finished products should be stored in a dry place at room temperature, avoid sunlight, and are prohibited from mixing with toxic and harmful substances. 4.2 Packaging: divided into five specifications of 0.5kg, 1.0kg, 5.0kg, 10kg and 25kg. 4.3 Each batch of packaged finished products should be accompanied by a quality certificate, which includes: manufacturer name, product name, quality indicators, batch number and production date. 4.4 The words "food additives" and specifications, shelf life, target users, consumption methods and consumption amounts should be firmly painted on the outer packaging.
4.5 It must not be mixed or transported with toxic and harmful substances during transportation, and should be protected from sunlight and rain. 4.6 Storage period: The shelf life of the original packaging is one year under the required storage conditions. Additional notes:
This standard was proposed by the State Drug Administration, the Ministry of Light Industry of the People's Republic of China, and the Ministry of Health. This standard is under the jurisdiction of the China Pharmaceutical Industry Corporation of the State Drug Administration, the Food Fermentation Institute of the Ministry of Light Industry, and the Food Hygiene Supervision and Inspection Institute of the Ministry of Health.
This standard was drafted by Shaanxi Xi'an Pharmaceutical Factory, Shaanxi Provincial Health and Epidemic Prevention Station, Henan Luoyang Food Additive Factory, and Luoyang City Health and Epidemic Prevention Station. This standard is equivalent to the 1981Ⅲ version of the US Food Chemicals Regulations (FCC). Approved by the State Drug Administration on February 22, 1988 and implemented on August 1, 198800mL, add 1% nitric acid to dilute to 50mL (each mL is equivalent to 0, 0.25, 0.50, 1.00ug of thione). The sample solution and each standard solution are introduced into the flame for measurement. The measurement conditions are: lamp current 6-7mA, wavelength 228.8nm, slit 0.15-0.2nm, air flow 5L/min, acetylene flow 0.4L/min, lamp head height 1mm, chlorine lamp background correction (it can also be adjusted to the best conditions according to the instrument model), and the standard curve is drawn for comparison with the corresponding concentration absorbance of cadmium content. 2.9.4 Calculation of analysis results
(A, - Ag)× V6
mg×1000×1000
Where:
Cadmium content in sample, %;
A—Content in sample solution for measurement, μg/mL; Content of thione in Ag reagent blank solution, μg/mL; V. Total volume of sample after processing, mL;
3 Acceptance rules
Sample mass, g.
**** (8)
3.1 This product shall be inspected by the quality inspection department of the manufacturer, and all products leaving the factory shall meet the requirements of this standard.
3.2 The user may verify the quality of the received products according to the inspection rules and test methods specified in this standard.
3.3 The weight of each batch shall not exceed the daily output of the manufacturer. 3.4 Sampling method: 2% of the number of bags in each batch shall be used to select samples. The small batch shall not be less than 3 bags. From the selected number of bags, use the sampling tool to reach into 3/4 of each bag and take out samples of not less than 100g. The taken samples shall be quickly mixed, divided into quarters, and placed in a clean and dry wide-mouth bottle with a ground mouth (the capacity shall not be less than 250mL). The bottle shall be labeled with the name of the manufacturer, production date, product name, batch number and sampling date, and sent to the laboratory for timely analysis.
3:5 If one of the test results does not meet the standard, the sample shall be doubled for testing. If one of the results of the re-test still does not meet the standard, the whole batch shall be determined as unqualified. 3.6 If the supply and demand parties have disputes over product quality and need arbitration, the two parties may negotiate the arbitration unit and conduct it according to the methods and acceptance rules specified in this standard. 4 Marking, packaging, transportation and storage
4.1 The packaging materials of zinc gluconate must meet the hygiene standards and requirements. The packaged finished products should be stored in a dry place at room temperature, avoid sunlight, and are prohibited from mixing with toxic and harmful substances. 4.2 Packaging: divided into five specifications of 0.5kg, 1.0kg, 5.0kg, 10kg and 25kg. 4.3 Each batch of packaged finished products should be accompanied by a quality certificate, which includes: manufacturer name, product name, quality indicators, batch number and production date. 4.4 The words "food additives" and specifications, shelf life, target users, consumption methods and consumption amounts should be firmly painted on the outer packaging.
4.5 It must not be mixed or transported with toxic and harmful substances during transportation, and should be protected from sunlight and rain. 4.6 Storage period: The shelf life of the original packaging is one year under the required storage conditions. Additional notes:
This standard was proposed by the State Drug Administration, the Ministry of Light Industry of the People's Republic of China, and the Ministry of Health. This standard is under the jurisdiction of the China Pharmaceutical Industry Corporation of the State Drug Administration, the Food Fermentation Institute of the Ministry of Light Industry, and the Food Hygiene Supervision and Inspection Institute of the Ministry of Health.
This standard was drafted by Shaanxi Xi'an Pharmaceutical Factory, Shaanxi Provincial Health and Epidemic Prevention Station, Henan Luoyang Food Additive Factory, and Luoyang City Health and Epidemic Prevention Station. This standard is equivalent to the 1981Ⅲ version of the US Food Chemicals Regulations (FCC). Approved by the State Drug Administration on February 22, 1988 and implemented on August 1, 198800mL, add 1% nitric acid to dilute to 50mL (each mL is equivalent to 0, 0.25, 0.50, 1.00ug of thione). The sample solution and each standard solution are introduced into the flame for measurement. The measurement conditions are: lamp current 6-7mA, wavelength 228.8nm, slit 0.15-0.2nm, air flow 5L/min, acetylene flow 0.4L/min, lamp head height 1mm, chlorine lamp background correction (it can also be adjusted to the best conditions according to the instrument model), and the standard curve is drawn for comparison with the corresponding concentration absorbance of cadmium content. 2.9.4 Calculation of analysis results
(A, - Ag)× V6
mg×1000×1000
Where:
Cadmium content in sample, %;
A—Content in sample solution for measurement, μg/mL; Content of thione in Ag reagent blank solution, μg/mL; V. Total volume of sample after processing, mL;
3 Acceptance rules
Sample mass, g.
**** (8)
3.1 This product shall be inspected by the quality inspection department of the manufacturer, and all products leaving the factory shall meet the requirements of this standard.
3.2 The user may verify the quality of the received products according to the inspection rules and test methods specified in this standard.
3.3 The weight of each batch shall not exceed the daily output of the manufacturer. 3.4 Sampling method: 2% of the number of bags in each batch shall be used to select samples. The small batch shall not be less than 3 bags. From the selected number of bags, use the sampling tool to reach into 3/4 of each bag and take out samples of not less than 100g. The taken samples shall be quickly mixed, divided into quarters, and placed in a clean and dry wide-mouth bottle with a ground mouth (the capacity shall not be less than 250mL). The bottle shall be labeled with the name of the manufacturer, production date, product name, batch number and sampling date, and sent to the laboratory for timely analysis.
3:5 If one of the test results does not meet the standard, the sample shall be doubled for testing. If one of the results of the re-test still does not meet the standard, the whole batch shall be determined as unqualified. 3.6 If the supply and demand parties have disputes over product quality and need arbitration, the two parties may negotiate the arbitration unit and conduct it according to the methods and acceptance rules specified in this standard. 4 Marking, packaging, transportation and storage
4.1 The packaging materials of zinc gluconate must meet the hygiene standards and requirements. The packaged finished products should be stored in a dry place at room temperature, avoid sunlight, and are prohibited from mixing with toxic and harmful substances. 4.2 Packaging: divided into five specifications of 0.5kg, 1.0kg, 5.0kg, 10kg and 25kg. 4.3 Each batch of packaged finished products should be accompanied by a quality certificate, which includes: manufacturer name, product name, quality indicators, batch number and production date. 4.4 The words "food additives" and specifications, shelf life, target users, consumption methods and consumption amounts should be firmly painted on the outer packaging.
4.5 It must not be mixed or transported with toxic and harmful substances during transportation, and should be protected from sunlight and rain. 4.6 Storage period: The shelf life of the original packaging is one year under the required storage conditions. Additional notes:
This standard was proposed by the State Drug Administration, the Ministry of Light Industry of the People's Republic of China, and the Ministry of Health. This standard is under the jurisdiction of the China Pharmaceutical Industry Corporation of the State Drug Administration, the Food Fermentation Institute of the Ministry of Light Industry, and the Food Hygiene Supervision and Inspection Institute of the Ministry of Health.
This standard was drafted by Shaanxi Xi'an Pharmaceutical Factory, Shaanxi Provincial Health and Epidemic Prevention Station, Henan Luoyang Food Additive Factory, and Luoyang City Health and Epidemic Prevention Station. This standard is equivalent to the 1981Ⅲ version of the US Food Chemicals Regulations (FCC). Approved by the State Drug Administration on February 22, 1988 and implemented on August 1, 1988
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