Quality assurance in testing laboratories, particularly when laboratories are licensed (see GB/T 15481), requires careful consideration of the accuracy of their measurement and analytical results and ensuring that the principles required to establish proof of accuracy are taken into account. Particular attention should be paid to the calibration of parameters associated with chemical analysis and materials testing, as major errors are caused by neglect or disregard of the basic principles of metrology that also apply to these areas. This standard gives general advice to laboratories or assessors faced with these problems. GB/T 15000.9-2004 Guidelines for working with certified reference materials (9) Calibration and use of certified reference materials in analytical chemistry GB/T 15000.9-2004 Standard download decompression password: www.bzxz.net
Quality assurance in testing laboratories, particularly when laboratories are licensed (see GB/T 15481), requires careful consideration of the accuracy of their measurement and analytical results and ensuring that the principles required to establish proof of accuracy are taken into account. Particular attention should be paid to the calibration of parameters related to chemical analysis and materials testing, since major errors are caused by neglecting or ignoring the basic principles of metrology that also apply to these areas. This standard gives general advice to laboratories or assessors faced with these problems.

ICS 71.540.30
National Standard of the People's Republic of China
GB/T 15000.9--2004/1S0 Guide 32:1997 Directives for the work of reference materials (9)-Calibration in analytical chemistry and use of certified reference materials(ISO Guide 32:1997,Calihraticr ir analytical chtmistry Enduse of certified reference matcria-s,IDT2004-12-31issued
General Administration of Quality Supervision, Inspection and Quarantine of the People's Republic of China Administration of Standardization of the People's Republic of China
2005-06-01implemented
GB/I ​​1500c.9—2004/ISO Gnide 32:1997 Figure
Standard core reference documents
Basic test points
Chemical analysis expansion to change the standard sequence to create selection
4.1 Types of analysis procedures
1.2 Other methods
= Calibration procedures
5.1 Type I methods
5.3 Type II methods
5.4 Overall comments
There are samples with over-standardUse of
G0 standard sample 1 working guide is divided into small parts: G10.14 Standard sample working guide
-GB/T 1>000.3--I54
Standard sample 1 working guide (2)
GH/T 1.i000, 3---1994
GB/T 15UUU:12003Www.bzxZ.net
Standard sample working guide (5)
Standard sample 1 working guide (4)
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Certification sample working guide)
.CB/T 15UUU.6
C:T 1500.7—2001
GB/T 15000.82003
GBT 15000, —2CC4
Standard sample 1 working guide ()
Standard product engineering rules
Standard product engineering rules (&)
Standard product space working guide (5)
This part is divided into (part 1).
tB/T 15000.9—2004/[S0 Cuide 32:1997 In the technical certification, the use of standard samples in the product is specified. Terms and definitions are specified. Note: Principles and statistical methods for product determination. Specifications and labels are specified. Detailed description of chemical standards. Special notes: Sample color and packaging. General description of standard samples. Requirements for the use of production methods. Please note that standard samples must be used in the production process. Use of certified standard samples in analytical chemistry. This part adopts 1S 32397 Calibration standards for analytical chemistry (English version). The following changes are made to the part 3: The previous part of the drama is bad!
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The technical requirements of the national standard selection committee of the central enterprise (SAC13) proposed: This part of the national standard difficult sample acceptance technical committee. The starting unit of this part: Quanju Standard Sample Nuclear Technical Committee, Xiamen Chaxin European Standard Sand Co., Ltd., Shanghai Leilong Technology Co., Ltd. The seven drafters of this part: Shang Hucai Qiang Guangwei, Hu Xiaozheng, Zhengwu, Ji Meng, Biao, Shu Ding, Liang Jiuyi T
GB/T15003.9--204/15O Gulde32:1997 Introduction
In October 1990, the International Laboratory Accreditation Organization (ILAC) General Assembly held in Torino, Italy, emphasized that the metrological significance of measurement results should be considered in the field of chemical calibration. Therefore, the meeting called for the development of a guideline for the use of certified standards for analytical chemistry, which was widely approved. The draft of the guidelines was drafted by the ILAC, which was approved by the General Assembly held in Canada in 2005. Since the standards need to be confirmed by the consistency of the results obtained in the analytical technology or the calibration of the standards, the new IEA guidelines are recommended to the international community. As the proposal for the development of the [S] guideline, ISO/RHMCO accepted the proposal and entrusted [SO/REMCO. 1 Working Group [S] Guidelines for the use of new certified samples for calibration in analytical chemistry, [C] 1956, with the approval of the National Standards Committee: The Technical Committee of the General Office of the Standardization Administration of China converted the [S] guideline into a standard for the use of new certified samples in analytical chemistry. The relevant experts of the organization will change the [S] guideline into a standard for the use of new certified samples in analytical chemistry. At the National Standards Committee meeting on February 23, 2004, the National Standards Committee approved the change. 1 Standard
Gn/T15CC0.9—2004/1N Guide 32:1997 Guide for Standard Samples (9)
Calibration and use of certified standard samples in analytical chemistry The calibration of analytical laboratories, especially when accredited by the accreditation authority (Ref. G13/=1541), requires more attention to the accuracy of measurement and analysis results. This standard introduces the principles of accuracy produced by the calibration process, and the steps involved in the calibration of chemical analytical instruments. Because the main requirements are often neglected or insufficiently applied, this standard gives some suggestions for development for laboratories or accredited laboratories facing this problem.
2 Normative references
The following documents are referenced in this part of B/T 5000 and are the references of this part. For any document with a specified period of time, its amendments (not including any errors) are not applicable to this part. However, the parties concerned shall study whether the latest versions of these documents can be used according to the selection of this part. For any document with a specified period of time, its version shall apply:
/T1.00%.2 Standard product working guide 3) Common product codes (1S (mide: 199B/T 15000.1 Standard sample guide) Principles and statistical methods for determining the value of standard samples (aectg tid38158)
Standard product standards (standard sample card machine label (S).F212300GB/T 15000.4
GR/T15000.7 Standard vehicle products. 1. Production number rules (7》General requirements for the ability of non-sample dust producers: ctISiuid-24:000)
B151m, standard 1# guide (3) Convenient use of certified standard samples (id:1s0.adc333n00)H/T1/81 General requirements for testing and testing the density of the testThe definition of CRM is 0.0. RM can be recognized by 1AG.>, RM can be used with the production of paint, or drift, or it can be used as the car's name. Except for a few notes, the M point is used in this aspect. The reading length can be selected from GH/T13.8, and there are also more twisted documents such as M: National Original Certificate of Use
L) Chemical users need to bring the materials or reagents they use, and they do not share the CRV standard. In fact, the CKM number is a batch of materials that have been observed by light, and the quality of the materials has been confirmed to be uniform. The analytical reagent instrument has been rated, and its inaccuracy is very large, so users need to pay attention to the special indications of various secretions to ensure that the reagents meet their needs 1
GB/T 15000.9—2G04/ISOGuide 32:1997 The uncertainty of the calibration results is composed of the above two parts. It is necessary to neglect either of them in one step and to compare the uncertainty of the calibration with the uncertainty required for the analysis (source case, and the two cases should be consistent). This comparison provides useful guidance in choosing between different calibration procedures. In the long run, it also provides valuable guidance for the implementation of methods and procedures. When physical measurements are made and tested, the recognition of the actual practice is solid. The authenticity of all chemical analysis instruments and/or measuring instruments to national standards is usually achieved through a system of calibration: This section will describe the relevant principles used to ensure the authenticity of chemical analysis instruments. In the past decade, the use of CRMs has become increasingly important. When CRMs are available, their use is expected to have a greater degree of stability. 4 Selection of calibration procedures in chemical analysis
4.1 Types of analytical procedures
First, the analytical procedures are divided into the following types: +||tt| |*Inflammatory type』
Type.
Each type involves,
·Basic method:
·Technical ten basic rules,
When the user classifies a method, he should carefully check and analyze all the parameters of the program, and should not be satisfied with seeking a method that is only suitable for the original method used under reasonable conditions. This method usually leads to low quality and needs to be reviewed and reviewed.
Control cannot make incorrect internal The force reaches the concave true faith (such as, the car muscle shows on!, the influence of the accurate factor of the chemical composition instrument is the branch estimated taxable change
the above-mentioned division is only used to identify the model mode, and the previous library is not used as a method for evaluation 4.1.1 ink type I
this type of method is used to identify the relevant rapid management and chemical contention data obtained during the branch process, so that the calculation of the parameters including this period is reliable, the moment
, the quality of the sample is checked, the test volume is determined, the amount of the precipitate is determined, and the natural volume of the product is determined, 4. 1. 2 Type II
This type of method is used in conjunction with a recognized test system that uses a known (theoretically non-linear) test system to compare the content of the analyte with a series of known standard samples (theoretically this must be done in a known manner). The sample signal should be linearly measured against the sample. This means that the sample series and the different samples should not be affected by other factors such as composition, format, etc. .The influence of the uncertainty can be ignored compared to these conditions. The analysis sequence can include: trying to make the best use of the method to minimize the sensitivity of the difference (such as spectral grade lubricants, sample treatment before analysis). The process of adopting the following forms: - converting the pure sample into a single product, for example, by acid digestion, removing the soil from the sample; - synthesizing a relatively complex calibration series of samples or using special items (such as preparation of a matrix phantom). + Limits should be given by
4.1.3 Type III
This type of method uses a precise analytical method or a method that is sensitive to the matrix (either type or method). The system is calibrated in detail and compared with the products. If the design effect is ignored, the product difference (correct shift) will be high. In order for this type of method to be appropriate, it must be used: CB/T15000.9-2C04/150Cuid:32:1997 Identification of commonly used product data, such as the amount of air, the structure of the product, the quality ... The first) sequence of identification witnesses has identified the product type:
, for the above-mentioned H identified 4 types of samples in violation of the 1RM series: "determined" internal "standard in the new process is reported that the total product is unacceptable to discuss the secret 4.2 other methods
low Shenzhen and cannot guarantee the source of the international unit! SI analysis method is not easy to obtain the results of the uncertainty. That is, it is still very important, and the results are prone to errors and losses. This will result in the price method being used by a single experimental case to analyze the drift. Shift, or in the limited temperature of the dynamic channel, the results of the local temperature of the pool will be produced at any point. The results must be provided with a special guarantee that the thermal conductivity of the result is not provided as a standard environment. The certification of this method should be detailed to ensure that the accuracy of the method is determined by some appropriate procedures and methods, and be guaranteed by a relevant rate and method: these methods are also the overall and current methods of the CD. 5 Calibration procedures
5. Type I method
On the selection card is the brush design to complete the completion of the new must be measured in the year not to promote the proposed The LRM is often used to confirm the validity of a method. It is important to note that the CRM assumes that the sample is measured on a daily basis and the two values ​​are compared with the standard. If there is a difference, the laboratory needs to ascertain the source and make an analysis. 5.2 Type I methods
For this type of method, the working sample is usually known to have a large amount of "discarded" analyte, and the measurement cannot be carried out in advance. The quality and volume of the selected analyte must be determined before the measurement. According to the book, the total plan of the original work is based on the various points: the spraying equipment is certified by the production. The test is carried out by the production personnel. The benefits are: the variable quantity system is accurate before the measurement (such as the above measurement must be sent, the pressure and humidity can stop the two parameters of the measurement system. For some branches, the uncertainty of this policy is the first of the constant elements - within this, the correct arrow chemical correction sequence: the pure material of the material must be guaranteed by the production class:
★ The color of the compound to be tested:
, the impurity element has been identified, such as the inorganic substance in the organic matter! : The North School Year is accurate. ||tt| |For "slippery equipment, pay special attention to the quality of the test, such as: the material being diluted
, to the old material that seems to be the same as the material being tested: the previous micro-cabin quality is closely related to the material being tested, and the material being tested may be inaccurate. The test air may fail to meet the standard: here, the key is to ensure that this is not the final result of the test. The price is not determined by the manufacturer. The manufacturer has a professional document to prove that it is suitable.
Liu Keda's RM is used for research and development with three stages
and the test sample service of the new plan can be calibrated by the manufacturer. This is what you do with the environment calibration rate flow The micro-method quality
GB/115055.9—2004/Ix1fuide32:19975.3 type and method
white This example is very sensitive to the body effect, therefore, the calibration procedure used must strongly consider these effects, so that the calibration method (R) used is desirable, so the selection of the RM used meets the necessary conditions: + The three normal characteristics of the RM are sufficiently similar to the sample, and there is no easy adjustment of the results with the calibration uncertainty required.
The appropriate (RM) is selected There are two needs to be installed between the domain optimization to obtain the total time and width of the six specifications (RV, the main points of the feeling are summarized as follows: in order to pursue more accurately, it is necessary to know the concentration of the new elements? How much is the uncertainty of the sample?
Consider the type of virtual, the cost of the raw material of the main ingredients "this kind of composition may have the "chemical \ rate average" effect on the separator?
Avoid the separation of the polarizer industry, the heart M and - products when other books can be unified on the type of his? For example, the shape of the collection group, the validity distribution, the metallographic refinement, etc.
5.4 General comments
Analyze the components of the control standards as much as possible, analyze the components of the cost, especially the calibration of the total purchase price (R or RM). This component must be calculated in advance: these costs do not prove that the calibration is inappropriate. The price calculation of the bed shop does not meet the basic requirements of the diagnosis and treatment. For example, the basic requirements specified in this part are not sufficient. Each method must specify the system requirements for each year. Regardless of the direction of the plan, the source must be The needs of all parties should be considered and the cost should be met. The accuracy of the instrument does not depend on the accuracy of the drug, the quality of the personnel, the cumulative error of the analysis period, etc.
6 Selection of certified reference materials (CRMT)
The first step is to select the required (R) CKM records available on the international market. The laboratory should search for the manufacturer's H:
. CMAR price:
+flexible, some table tennis skills: the most important point is to determine the special field (M) recommended by the scientific publications or the most important point: - G3/T' 153JJ. 7.
Laboratory assurance is the core of the inspection area: the value of the element involved is not the same as the standard, the order of the mark has an appropriate metrological reliability level (G/! 13000,3), is well documented (G3/5330.,. In principle: determined without any limitation of any additional. Not considered accurate will be confirmed.
As for the knowledge of the laboratory, in order to obtain the complete relationship between the RM and the product under all circumstances (RM and the reference is not the only one who has the right to be accepted by the technical personnel). Reasonable external security is acceptable to you. See you to order the new offer
Make the LRM available on the market with the guarantee: "the highest quality assurance:
■ overall price-performance ratio.
CB/T15000.9—2004/1S0Guid e32.1997 Therefore, the decision not to use the combined, available, judged (R) experimental document should explain this choice in its process as much as possible, 7 internal standard sample RM> use
If the market cannot lose the CRM that meets the needs specified in the experimental plan, the internal RM is developed under the white light: Xiao Ding This choice brings long-term and product policy exploration, and he includes the use of sustained in-depth resources and experience. Therefore, the laboratory has the following possibilities;
, and also has some ability to develop this new (RM) first contact: Liu Gan a relative, KM. Clear market demand for each product is not more than ten years, manufacturers often do not consider common development needs: there is a time requirement for the use of the system, laboratories jointly project day; at the same time, can lead to the RM production of your internal laboratory of other departments RV. Establish a joint external quantity guarantee support. Internal M is allowed to be no less accurate than CRM, but some of them must have better applicability. Each RM should meet the following conditions:
, can be traced back within the year;
has recognized uniformity of the problem; internal confidence has been confirmed; ensure that the uncertainty required by the standard can be adjusted according to the requirements, and the uncertainty required by the imaginary value can be reduced: for the internal M, it is usually necessary to use the type 1 method to eliminate the uncertainty of the numerical value. It is best to use the RM to make it recognized: in this case, it is useful for the department to save materials (RM, for a series of types, the ancient method (for a series of types) can be adopted to check the standard, because this case is more Comparison may increase the uncertainty of RM. This is why: the internal RM is not evaluated and the uncertainty is not determined by the sample. If it is not feasible to develop an internal RM for the purpose of combination and verification, the user must re-select the program and use a new method that does not require the use of a new RM. GB/T15000.9—2004/150 ...
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