This standard specifies the diagnosis and treatment principles of cosmetic photodermatitis. This standard applies to cosmetic-induced photodermatitis. GB 17149.6-1997 Diagnosis and treatment principles of cosmetic photodermatitis GB17149.6-1997 Standard download decompression password: www.bzxz.net

GB 17149.6—1997
This standard is specially formulated to cooperate with the implementation of the "Regulations on Hygiene Supervision of Cosmetics" of the People's Republic of China. The diagnostic criteria and treatment principles stipulated in this standard only cover photosensitive dermatitis caused by cosmetics. This standard shall be implemented from December 1, 1998. Appendix A of this standard is the appendix to the standard. wwW.bzxz.Net
Appendix B of this standard is the appendix to the suggestion. This standard is proposed by the Ministry of Health of the People's Republic of China. The drafting units of this standard are: PLA Air Force General Hospital, the Second Affiliated Hospital of Dalian Medical College, the First Affiliated Hospital of Nanjing Medical College, and Peking Union Medical College Hospital.
The main drafters of this standard are: Huang, Li Ruikang, Liu Wei, Zhao Bian, and Yuan Zhaozhuang. The Chinese Academy of Preventive Medicine, the technical management unit entrusted by the Ministry of Health, is responsible for the interpretation of this standard. 442
National Standard of the People's Republic of China
Diagnostic criteria and principles of managementof photosensitive dermatitis induced by cosmeticsGB17149.6--1997
Cosmetic photosensitive dermatitis refers to inflammatory changes in the skin caused by light exposure after the use of cosmetics. It is a phototoxic reaction or photoallergic reaction of the skin and mucous membranes caused by the photosensitive substances in the cosmetics. 1 Scope
This standard specifies the diagnosis and treatment principles of cosmetic photosensitive dermatitis. This standard is applicable to photosensitive dermatitis induced by cosmetics. 2 Referenced standards
The provisions contained in the following standards constitute the provisions of this standard through reference in this standard. When this standard is published, the versions shown are valid. All standards will be revised, and parties using this standard should explore the possibility of using the latest version of the following standards. GB17149.2—1997 Diagnostic criteria and treatment principles for cosmetic contact dermatitis 3 Diagnostic principles
There is a clear history of cosmetic contact, and photosensitive dermatitis occurs in the corresponding parts after exposure to light. If necessary, it can be combined with the light patch test, see Appendix A, to exclude photosensitive dermatitis caused by non-cosmetics. 4 Diagnostic criteria
4.1 There is a clear history of cosmetic contact and light exposure. 4.2 The skin lesions mainly occur in the light-exposed parts after the use of cosmetics. 4.3 The skin lesions have various forms, and erythema, papules, and small blisters may appear. Subjective symptoms are itching; chronic skin lesions may be infiltrated, thickened, and lichenified. 4.4 When it occurs in the oral mucosa, it may manifest as swelling, cracking, exudation, etc., and the lower lip is more common or more severe. 4.5 The course of the disease can be prolonged, and rashes may still occur after stopping the use of cosmetics, and the disease may recur after contact with photosensitive substances. 4.6 The cosmetic light patch test is positive, see Appendix A. 4.7 Exclude photosensitive dermatitis caused by non-cosmetics. 5 Treatment principles
5.1 Remove cosmetics left on the skin promptly. 5.2 Stop using cosmetics that cause disease and avoid exposure to light. 5.3 According to the condition, treat photosensitive dermatitis symptomatically. Approved by the State Administration of Technical Supervision on December 15, 1997 and implemented on December 1, 1998
GB 17149.6-1997
Appendix A
(Appendix to the standard)
Skin light patch test method
A1 Principle: Expose to light on the basis of skin patch test. If there is photoallergy to the patch test substance, delayed photoallergic reaction of the skin may occur after exposure to light.
A2 Method and Determination of Reaction Degree
A2.1 Place the suspected photosensitizer on the patient's back for three patch tests at the same time or use patch test tape to test several different test objects at the same time, see Appendix A of GB17149.2--1997.
A2.2 Light source: Generally, a high-pressure mercury gas quartz lamp or a water-cooled quartz lamp is used to measure the minimum erythema dose (MED) on the forearm or abdomen. A2.3 After 24 hours, remove the three patch test objects. One of them is immediately covered with a light shielding material to avoid any light exposure as a control; the second place is irradiated with a sub-erythema dose lower than the MED (mainly UVB); the third place is irradiated with a light source filtered by ordinary window glass (mainly UVA, the time is 20 to 30 times the MED). A2.4 Observe the results 24, 48, and 72 hours after irradiation. The reaction degree assessment is the same as GB17149.2. A3 Result determination: For those who have a positive reaction in the unexposed area, the diagnosis can be made according to GB17149.2; if a positive reaction only occurs in the area exposed to sub-erythema dose, it can be determined as a phototoxic reaction; if a positive reaction only occurs in the area exposed to the light source filtered by the window glass, it can be determined as a photoallergic reaction; if both of the latter two are positive, it means that there is both a phototoxic reaction and a photoallergic reaction. Appendix B
(Suggested Appendix)
Common allergens and their patch concentrations of cosmetic photodermatitis Table B1 Common allergens and their patch concentrations of cosmetic photodermatitis
Benzophenones
p-Aminobenzoic acid (PABA) Muskxylene
fenticlor
sulfanilamide
formaldehyde
musk ambrette)
rivanol
6-methylcoumarin
bithionol
hexachlorophene
thiourea
chlorhoxidine diacetate (acetic acid washing bithitai) methylene blue
lemon oil oil)
cinnamaldehyde
tribromsalan
triclosan
triclocarban
moskene
patch concentration, %
GB17149.6—1997
Table B1 (end)
tetrachloro salicylanilide sandalwood oil
musk ketone
chlorpromazine hydrochioride promethazine hydrochloride diphenhydamine hydrochloride hydrochloride)eosin
fluorescein
patch concentration, %
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