This standard specifies the criteria for correctly determining the disease areas and scientifically classifying disease areas. This standard is applicable to the determination and classification of disease areas. GB 16395-1996 Standard for determination and classification of disease areas for Kaschin-Beck disease GB16395-1996 Standard download decompression password: www.bzxz.net

National Standard of the People's Republic of China
Criteria of decide and delimitof Kashin-Beck disease endemic area
Criteria of decide and delimitof Kashin-Beck disease endemic areaSubject content and scope of application
GB16395—1996
This standard specifies the standards for correctly deciding Kashin-Beck disease endemic areas and scientifically classifying endemic areas. This standard is applicable to the determination and classification of endemic areas of Kashin-Beck disease. 2 Referenced standards
GB16003 Diagnostic standards for Kashin-Beck disease
3 Endemic area determination standards
Endemic areas should be determined based on typical cases of local disease (see GB16003) and natural villages (towns) as units. Areas with the following two conditions are determined as endemic areas.
3.1 It constitutes an epidemic, and the prevalence of clinical degree and above in the whole population is >5%. 3.2 Cases of multiple and symmetrical bone end changes in hand X-rays among people under 16 years old. 4.1 Classification by severity of disease in wards
4.1.1 Mild ward: 10% prevalence of clinical grade 1 or above in the whole population, or X-ray detection rate of children aged 7 to 14 years old <10%. 4.1.2 Moderate ward: 10% to 20% prevalence of clinical grade 1 or above in the whole population, or X-ray detection rate of children aged 7 to 14 years old 10% to 30%.
4.1.3 Severe ward: 20% prevalence of clinical grade I or above in the whole population, or X-ray detection rate of children aged 7 to 14 years old >30%. 4.2 Classification of new and historical wards
4.2.1 New ward: The local population has not had the disease in the past. All current cases of grade I or above are among the population under 20 years old. After epidemiological investigation, clinical survey and X-ray examination, those who meet the epidemic characteristics of the disease and meet the conditions for determining wards in this standard can be determined as new wards. 4.2.2 Historical ward: According to historical data, it has been determined as a ward. According to clinical survey, there are no patients with grade I and 1 in the population under 25 years old, and the detection rate of grade I patients is less than 3%. There are no cases of grade 1 and above in the population under 20 years old; the X-ray detection rate of children aged 7 to 14 is less than 5%, the detection rate of bone ends is less than 3%, and there are no cases of metacarpal (ten-ten) changes, nor are there cases of premature closure of the metacarpals and triads. Approved by the State Administration of Technical Supervision on May 23, 1996 and implemented on December 1, 1996Www.bzxZ.net
GB16395--1996
Appendix A
Instructions for the correct use of the standard
(Supplement)
A1 The "typical cases of local onset" mentioned in this standard refer to cases of clinical grade I and above occurring in the current place of residence, or cases with multiple, symmetrical bone end changes on the hand X-ray films of children and adolescents. A2 The determination of the disease area and the classification of disease area types are based on natural villages (townships). A3 The number of children aged 7 to 14 years old who undergo X-ray examinations shall not be less than 50 (if a natural village or town has less than 50 children aged 7 to 14 years old, the number shall be supplemented by children of the same age in neighboring villages or towns). For those with more than 50 children, stratified random sampling shall be conducted, and the number of people who undergo X-ray examinations shall not be less than 7 for each age group. A4 After several years of evolution, disease areas may become historical disease areas or mild disease areas. In historical disease areas or some mild disease areas, this disease may not be prevalent, so the prevalence of grade 1 and above may be <5%, and the X-ray detection rate of children aged 7 to 14 years old is also <5% (or even undetectable). Additional notes:
This standard was proposed by the Ministry of Health of the People's Republic of China. This standard was drafted by the Shanxi Institute for the Prevention and Control of Endemic Diseases. The drafters of this standard were Zhou Zhenlong, Jiang Zhenpu, Chen Yongxiang, Ning Guodong, and Deng Tianen. This standard is interpreted by the China Research Center for the Prevention and Control of Endemic Diseases, the technical unit entrusted by the Ministry of Health. 476
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