JJG 969-2002 Verification Procedure for Gamma Radioimmunoassay Counters JJG969-2002 Standard download decompression password: www.bzxz.net
This procedure applies to the initial verification, subsequent verification and in-use inspection of single-probe and multi-probe gamma radioimmunoassay counters.

National Metrology Verification Regulations of the People's Republic of China JJG 569—2002
Y Radioimmunoassay Counters
Gamma Radiuinmmunassay Counters2002-04-15 Issued
2002-07-01 Implementation
General Administration of Quality Supervision, Inspection and Quarantine
Main drafters of this regulation:
Tang Fangdong
Tan Qiukang
Xu Shuxiang
JIG969
(Shanghai Metrology and Testing Technology Research Institute) (1 Shanghai Jiken Testing Technology Research Institute)
(Shanghai Nanyang Rescue Immunity Testing Center) 2
References
3 Terms and units of measurement
3.1 Terms
3,2 Units of measurement
4 Overview
Metrological performance requirements
Activity response
Repeatability
Linearity of activity response
General technical requirements
Mechanical characteristics and electrical safety characteristics
Test room
7 Bean counting equipment system
Verification parts
Verification requirements and verification methods
Processing of verification results
Verification period
Verification certificate original record format
JH; 569—2002
JJG969--2002
Verification Regulation of GammaRadioimmnnoassay Counters
JJG 969-- 2002
This regulation was approved by the General Administration of Quality Supervision, Inspection and Quarantine on April 15, 2002, and came into force on July 1, 2002.
Original unit: National Technical Committee for Ionizing Radiation Metrology Drafting unit: Shanghai Institute of Measurement and Testing Technology This regulation is entrusted to the National Technical Committee for Ionizing Radiation Metrology for interpretation 1 Scope
J1G969-·2()2 www.bzxz.net
? Radioimmunity Counter Verification Procedure
This regulation is applicable to the initial verification, subsequent control and use of radioimmunity counters with single-probe and multi-probe. The running count range is 3000/min2 00000/min: Commonly used nuclear matter is\12 Cited documents
This regulation cites the following documents:
GB10255-199%Y Radioimmunocounter GB4960-1296 Material Science and Technology Lecture 3
GB/T4080-1983 "Test Dimensions for Radioactivity Test" G (Shanghai) 44--1999 "Revised Radioimmunocounter" 3 When using this regulation, please pay attention to using the currently valid versions of the above-mentioned cited documents. 3 Technical understanding and measurement units
3.1 Radioimmunoassay A microanalytical method that uses the specific reaction between radioactive nuclides labeled antigens and a limited amount of corresponding antibodies to quantitatively determine the concentration of the substance to be measured:
3.1.2 Activity response r:
The instrument response with the smallest efficiency (after correction for background) divided by the activity of the standard source, 3.2 Measurement units
The symbol of the activity response is zero; R, measurement unit: Bu-1.s- The symbol of the background: G: measurement unit :i-1
Symbol of repeatability: 5, Unit of measurement: dimensionless Symbol of nonlinear response:, Output: none Overview
The radioimmunoassay counter (hereinafter referred to as radioimmunoassay counting instrument) is mainly composed of a detector, a counting device and a data processing system: Na(T) The radioimmunoassay detector composed of a body and a photomultiplier tube converts the new radiation into an electrical signal, which is processed electronically and output through the counting device or input into the data processing system: The radioimmunoassay counter is used in the determination of radioactivity in radioimmunoassay and is an important analytical instrument in nuclear medicine. 5. Metrological performance requirements
During the first verification, the background counting rate of the newly manufactured radioactive-free counter should be less than 8> counts m, and the background counting rate of the in-use version 1
JJC9692002
negative ten teaching instrument should be less than -decimal/rin. During the continuous verification and the inspection in the middle of the use, the background digit of the radioactive-free counter should be less than the indicated addendum mm52 activity
formula (20±5 before the change). The activity change response of the counter to 1 nuclide or 9" nuclides should not be less than 0.-5. 3 Vertical repeat
The radiation immunity counter shall be within its measuring range, time: the measured object shall be measured 10 times in a row, the relative standard of a single reading shall not exceed:
5.4 The non-variable response of the radiation immunity counter shall be within the measuring range (), the non-slow response of the activity shall not exceed 85%
6 General technical requirements
6.1 Appearance
The radiation immunity counter 1 must be manufactured by a different factory, and the patent, brand number, and domestic instruments shall be certified for production date, etc. Clearly marked, with instructions for use and, "second inspection certificate, the inspection should be accompanied by the inspection certificate! 6.2 Mechanical properties and electrical safety characteristics
The mechanical and electrical safety characteristics of the radiation immunity counter shall comply with the requirements of GB1025S-196. G,3 Test plan
The test plan of the radiation immunity counter shall be free of radioactive pollution and easy to decontaminate. 7 Instrument control
Instrument control includes: The first choice is: After the system is determined to use the test 7.1 Qualified parts ||t 7.1.1. Activity standard [nuclides or I nuclides standard source. 7.1.1.2 Standard source production range is (100-3000) B1.1.1.3 The source of the standard source is not specified by the teacher. 5, -3). 7.1.1.4 Standard source transformer (the size of the test tube shall meet the requirements of Table 1. Table 1 Test size
Goodness imrr
(Philosophical material)
The original size
.55 ± 3
All the lines
small compensation maximum 1. (Tan Gongwang
.-.2 Specification is the operation of the companion
G: 69-2O2
7.21 Teacher environment 2 source: equal gas absorption rate 0.23?.2.2 During the test, the ambient temperature is (2) above 5), and the guarantee should be: the discharge counter should be guaranteed to be always above the standard.2.3 The power supply is stable, and there is no external electric field, magnetic field and the ten currents of the positive epidemic. 7.2 Verification items rise and fall
7.2.1 Pet service
Table? Verification Item list
Yes
Previous shop
Active response nonlinearity
: "+", "-
7.2.2 Background
First calibration
Optional
Subsequent calibration
Use the intermediate inspection
Put the sample without paired pieces on the counter for one time, and the test time is 60, and the continuous measurement is determined according to formula (1) to calculate the value of the technical level.
Formula 2:,.-Change the background failure rate of the effective meter, min-!,--: the reading value of the test product, min
Test product number
7.2.3 Activity response
Measure the activity of a standard source or a standard radioactive source with an activity of 5 Us, and measure it for five times in a row. Formula (2) Activity response R-AXG)
Activity, r,
average value of the center value, mm;
Count rate of the radioactive source counter, min-12 Activity signal of the standard source: Bg
7.2. Repetitive attenuation
Measure the activity of a standard source or a standard radioactive source with an activity of 15 Us, and measure it for five times in a row. Formula (5) Calculate the relative standard deviation of the single measurement to 3
JJG969—2002
12(x: - x) 1%
i--repeatability. Sign;
--arithmetic mean of the measured results, mi-l
x, the ith single value, min
7.2.5. Moderate response nonlinearity
In the range of (100~3000) Bg, select 5 13【standards or 91 standards with upper and lower limits and uniform distribution of activity values, and measure on the radiation immunity meter. Each measurement time is 605, and each source is measured 10 times continuously. The measurement point with activity value close to 500 Bg is taken as the reference point. The activity response linearity of each measurement point is calculated according to formula (6), and the one with the largest absolute value is the activity response nonlinearity of the radiation immunity meter: 1
×100%
Where: L is the activity response nonlinearity of the th measurement point, R is the activity response of the th measurement point, and R is the activity response of the th measurement point.
is the activity response of the reference point.
了.3 Handling of verification results
了.3.1 According to the provisions and requirements of this regulation, a verification certificate shall be issued to the radioimmunoassay counter that has passed the verification. (4)
7.3.2 According to the provisions and requirements of this regulation, a verification result notice-1 shall be issued to the radioimmunoassay counter that has failed the verification, and the failure forecast period shall be noted.
7.4 Verification cycle
? The verification cycle of the radioimmunoassay counter shall not exceed 2 years in general. 4
: Contents of the verification certificate
1 Verification conditions
JIG969—20H2
Verification certificate and original record format
1 Name of the standard source nuclide used for verification, scope of use and non-spreading limit 7.2 Verification environmental conditions
2 Verification results
2.1 Background
2.2 Activity response
2.3 Gravity attenuation
2.4 Activity response nonlinearity
|、Format of original verification record
Inspection form:
Mauge ground:
Standard core:
Environmental conditions:
Cost: (-00 yuan)
Appropriate response: (#=605, 4=
Reproducibility: (=60s)
Ping and position:
Four active non-active
Activity range:
Sample name:
Expanded uncertainty
Pinggouqiao
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